Aeolus Pharmaceuticals has started a Phase 1 clinical trial to evaluate a new version of AEOL 10150 as a treatment for delayed effects of acute lung radiation exposure(Lung-ARS). The open-label, single-center Phase 1 trial will evaluate the safety, tolerability and pharmacokinetics in healthy individuals of increasing doses of AEOL…
Trial of AEOL 10150 as Treatment for Lung Radiation Exposure Gets Under Way
If you have a chronic illness like pulmonary fibrosis it’s easy to focus on the future instead of living your life in the moment. What’s the future of pulmonary fibrosis treatment? Find out more. Our resident columnist Kim Fredrickson knows this all too well and in her latest article “Don’t Let Your Diagnosis…
PBI-4050 is a safe and effective therapy for patients with idiopathic pulmonary fibrosis (IPF), according to results of the now-completed Phase 2 clinical trial developed by ProMetic Life Sciences. The open-label, single-arm, Phase 2 study (NCT02538536) enrolled 40 IPF patients at six different sites in Canada to investigate the safety,…
I always have been fairly independent. When I was little I played outside alone in a small town where the “scary stories” of a big city just didn’t happen. I was lucky enough to buy my first car very early in my teenage years, which gave me…
We breathe every day. For some of us, this process is simple and we don’t think too much about it. For others, it’s a constant struggle that requires a lot of concentration and effort. For all of us, it’s important we’re aware that there’s a right—and wrong—way to breathe. If you…
Lung cells of patients with idiopathic pulmonary fibrosis (IPF) have higher than normal levels of two cytokines, small proteins crucial to the functioning of the immune system, according to a study. The researchers also discovered higher than normal levels of the cytokines interleukin 33 (IL-33) and thymic stromal lymphopoietin (TSLP)…
People with idiopathic pulmonary fibrosis (IPF) who have low levels of oxygen in the blood (hypoxemia) might be closer to having a new treatment option with the launch of a Phase 1 trial evaluating GBT440 in healthy volunteers, and two Phase 2 tests in select IPF patients. Global Blood…
Traveling with pulmonary fibrosis (PF) can be very challenging if you require oxygen. You need to be sure you have enough oxygen for your journey, plus extra in case of any hold-ups or unforeseen circumstances. Usually, traveling short distances doesn’t really pose many problems but long distance car travel or traveling by…
I’m not big on hope, even though I have a sign that says “hope” on my porch year-round. Are you thinking “Wait! How can she say that? I want to be encouraged here!” I’m not big on attaching hope to:…
Learning that a loved one has a chronic illness is devastating, and even more so if that illness is likely to cut their life short. Everyone deals with the death of loved ones different, the grieving process is varied and there is no wrong or right way to go about…
