Blocking JNK Pathway May Ease Lung Fibrosis in IPF Patients, Study Suggests
Blocking a particular pathway — called c-Jun N-terminal Kinase (JNK) — may reduce lung remodeling and fibrosis, researchers said in a multi-part study reporting the effects of a JNK inhibitor in a mouse model and, subsequently, in a clinical trial involving patients with idiopathic pulmonary fibrosis (IPF). The study, “JNK inhibition reduces lung…