As we launch into Pulmonary Fibrosis Awareness Month this September, I personally believe there’s a lot that can be done to educate others and to raise the profile of this cruel and life-threatening lung disease. I look forward to sharing in an upcoming column more tangible ideas about how…
Japanese people diagnosed with both pulmonary fibrosis (PF) and emphysema appear to carry a single genetic mutation that contributes to the development of both conditions, a study reports. This mutation was linked to lower levels of the anti-inflammatory…
In the U.S., idiopathic pulmonary fibrosis (IPF) mortality rates decreased from 2004 to 2017, a new study shows. The data suggests the decline might be partly explained by a decline in smoking, but further research is needed to better understand the factors contributing to this trend. The study, “Mortality Trends…
Galecto‘s investigational compound GB0139, now in an enrolling clinical trial, has been designated an orphan drug by the U.S. Food and Drug Administration and the European Medicines Agency (EMA) as a potential treatment of idiopathic pulmonary fibrosis (IPF). GB0139 (formerly TD139) is an inhaled small molecule inhibitor of…
Receiving a pulmonary fibrosis diagnosis is a life-changing event. Accepting this new reality may initially seem impossible. There are so many new things to consider that never were on the radar before they suddenly became important. In addition to finding your footing in the present, you must…
AbbVie will assume development of Morphic Therapeutic‘s alpha v beta 6 (αvβ6) integrin inhibitors as potential treatments for idiopathic pulmonary fibrosis (IPF) and other fibrotic diseases, exercising a licensing option under an earlier research partnership between the companies. Integrins control a wide variety of cellular processes, including…
At some point in everyone’s lives, we feel overwhelmed by the pressure to perform, whether it’s getting good grades at school, excelling at playing an instrument, or receiving a promotion at work. Many of these are normal pressures one expects throughout their lives. However, patients with idiopathic pulmonary fibrosis (IPF),…
Raremark, an online rare disease patient community, has launched a digital platform called Xperiome, aimed at streamlining the search for new medicines for rare disorders and incorporating more patient input into research. The goal is to help the pharmaceutical industry deliver innovative new therapies faster and smarter, the…
Four years of monitoring clinical use of Ofev (nintedanib) by people with idiopathic pulmonary fibrosis (IPF) has found no new safety concerns, a database study found. Treatment safety and tolerability were consistent with findings reported in pivotal trials, with non-severe diarrhea continuing to be the most common side effect noted,…
People with idiopathic pulmonary fibrosis (IPF) who are treated with either Ofev (nintedanib) or Esbriet (pirfenidone) report similar satisfaction with their medications, a new study suggests. The study, “Patient expectations, experiences and satisfaction with nintedanib and pirfenidone in idiopathic pulmonary fibrosis: a quantitative study,”…
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