Boehringer Ingelheim‘s Ofev (nintedanib) preserved the lung function of nine idiopathic pulmonary fibrosis patients waiting for a lung transplant, a study reported. The research, “Safety of nintedanib before lung transplant: an Italian case series,” appeared in the journal Respirology Case Reports. A lung transplant is…
Ofev Preserves Pulmonary Function of IPF Patients Awaiting a Lung Transplant, Study Finds
If you have read my previous columns, you may be aware of how much things have changed for me since my idiopathic pulmonary fibrosis (IPF) diagnosis. My current life is nothing like the one I had before, and that took me some time to accept. But I am…
An Australian study showed that AD-114, an investigative therapy for idiopathic pulmonary fibrosis (IPF) developed by AdAlta, prevented the infiltration of immune cells and collagen build-up in lung cells from IPF patients. AD-114 also reduced fibrotic injury in a mouse model. The study, “Anti-fibrotic Effects of…
Trying to stay fit is extremely important for a PF patient. This is easier said than done. It is difficult to lose weight when you don’t move a lot, and it is hard to exercise when you feel tired and worn out all the time. I’ll bet you…
The Pulmonary Fibrosis Foundation’s annual Broadway Belts for PFF! fund-raiser generated a record $350,000 this year. This brought the amount raised in the event’s eight years to nearly $1.2 million. The proceeds support the foundation’s work and research seeking a cure for pulmonary fibrosis. Julie Halston, a Broadway star and comedienne,…
When you are diagnosed with a life-threatening illness such as idiopathic pulmonary fibrosis (IPF), the choices about how you live your life suddenly becomes illuminated. Since IPF literally steals a patient’s ability to breathe, the prognosis of this disease is not very good, plus there is no cure.
A lung transplant can benefit those whose pulmonary fibrosis (PF) stems from Hermansky-Pudlak syndrome (HPS), a study indicate. The study, “Clinical management and outcomes of patients with Hermansky-Pudlak syndrome pulmonary fibrosis evaluated for lung transplantation,” was published in the journal PLOS One. HPS is a rare…
Reata Pharmaceuticals’ bardoxolone methyl significantly improved the exercise capacity of patients with idiopathic lung disease (ILD) associated with pulmonary hypertension (PH), a Phase 2 clinical trial showed. The ongoing LARIAT study (NCT02036970) is evaluating the safety and efficacy of bardoxolone in about 165 patients whose PH is associated with…
As someone living with idiopathic pulmonary fibrosis (IPF), I have enjoyed connecting with others on a similar illness trajectory as me, as well as those living with different kinds of illnesses, including different forms of pulmonary fibrosis. We all have things in common, as well as things we…
Researchers identified a small group of genes that may promote idiopathic pulmonary fibrosis (IPF) after analyzing gene expression profiles in fibroblasts isolated from the lungs of patients with the disease. The study, “Global Gene Expression Analysis in an in vitro Fibroblast Model of Idiopathic Pulmonary Fibrosis Reveals Potential Role…
