6 Pulmonary Fibrosis Causes and Risk Factors

6 Pulmonary Fibrosis Causes and Risk Factors

Pulmonary fibrosis is a lung disease where the tissue which surrounds the air sacs (called alveoli) become scarred, making it difficult for oxygen to get into the bloodstream. Since there are various causes and risk factors for pulmonary fibrosis, we’ve compiled a list of some of the main causes and…

How Do You Counter Feelings of Helplessness?

For the friends and colleagues who see me regularly, many of you know this week was particularly challenging for me. In addition to recovering physically from my latest medication dose and being sick, I also was dealing with the emotional swings of the steroid injections. My puppy…

LOXL2 Protein Helps Promote Lung Scarring, Study Shows

The LOXL2 protein plays a critical role in the development of idiopathic pulmonary fibrosis (IPF) by helping promote lung tissue scarring, according to a study. LOXL2 is one of a family of proteins important to extracellular matrix (ECM), a non-cell component essential for providing structural and biochemical support to tissues and organs. LOXL2…

Pulmonary Fibrosis Foundation Publishes Updated PF Information Guide

The Pulmonary Fibrosis Foundation (PFF), a trusted resource for the estimated 200,000 Americans with pulmonary fibrosis (PF), has published its new “Pulmonary Fibrosis Information Guide“ —  which gives patients, family members and healthcare providers a better understanding of PF as well as idiopathic pulmonary fibrosis (IPF). The 36-page guide, available online here and…

Actors Gather in New York for PF Fundraising Event: ‘Broadway Belts for PFF!’

Broadway stars at New York City’s Edison Ballroom helped raised a record $250,000 to support the battle against pulmonary fibrosis (PF) in the 7th annual ‘Broadway Belts for PFF!’ To help boost funding for PF research, actress and dedicated Pulmonary Fibrosis Foundation (PFF) advocate Julie Halston hosted the benefit show, which featured Grammy and Tony award winners. Halston…

Clinical Trial Shows TD139 as a Promising Therapy Against Pulmonary Fibrosis, Maker Says

Clinical trial results indicate that inhaled TD139 is an effective, safe and well-tolerated treatment for idiopathic pulmonary fibrosis (IPF), its maker, Galecto Biotech AB, has reported. The phase 1b/2a clinical trial (NCT02257177) was divided into two parts. Part 1 was a randomized, double-blind, single-center, placebo-controlled, single ascending dose phase 1…

Synairgen Releases Data Showing Early Potential for LOXL2 Inhibitor to Treat IPF

Synairgen released further positive data from its lysyl oxidase-like 2 enzyme (LOXL2) inhibitor program to treat idiopathic pulmonary fibrosis (IPF), being conducted in collaboration with Pharmaxis. A Phase 1 clinical trial is set to start this year, if toxicology studies are successfully completed. Synairgen and Pharmaxis entered a collaboration in August…