MiRagen Therapeutics‘ MRG-201 has reversed fibrosis in mice with pulmonary fibrosis, according to a presentation the company prepared for the 76th annual meeting of the Society for Investigative Dermatology in Portland, Oregon. The biopharmaceutical firm develops fibrosis treatments that target microRNAs, small molecules that control whether genes are switched on or…
MRG-201 Reversed Fibrosis in Mice, miRagen Says in Report for Conference
Ofev (nintedanib) is a drug used in the treatment of idiopathic pulmonary fibrosis (IPF). The anti-fibrotic therapy is made by the pharmaceutical company Boehringer Ingelheim and was approved by the FDA in October 2014 and by the European Commission in January 2015. MORE: New knowledge about Ofev and Esbriet may…
Natural gene variants, called polymorphisms, may explain why some patients with systemic sclerosis also develop pulmonary fibrosis (PF). The study, “The status of pulmonary fibrosis in systemic sclerosis is associated with IRF5, STAT4, IRAK1, and CTGF polymorphisms,” appeared in the journal Rheumatology International. PF is one of the leading…
Since being diagnosed with idiopathic pulmonary fibrosis (IPF), it has been interesting to observe how certain movie quotes seem to have much more meaning than they did prior to my diagnosis. I tend to watch movies these days seeking out characters who can relate to what it…
Pulmonary fibrosis (PF) is a chronic lung disease where the tissue in the lungs becomes scarred and stiffens over time. Like all diseases, PF does not discriminate and there have been many celebrities who have suffered from the condition. Sadly, some have lost their lives to the disease. According to…
An investigative therapy for idiopathic pulmonary fibrosis (IPF) based on inhibiting two proteins, including the cannabinoid CB1 receptor, shows potential for halting fibrosis progression, and greatly improved survival in a mouse model for human IPF. The study, “Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis,” was published…
I try to stay positive while also being realistic about the hardships that go with using supplemental oxygen 24/7. But this week I’m irritated and worn-out from the hassles I deal with daily. Here’s me being real. I’m tired of: Having to fight with my insurance and…
As the weather turns warmer, many of us will be thinking about vacations and traveling. While traveling with a lung disease does require some careful consideration, having a lung disease doesn’t mean that you have to be confined to the house. The British Lung Foundation has…
Pulmonary fibrosis is a chronic lung disease where the tissues in the lungs become hard and stiff, causing respiratory difficulties. MORE: The treatment options for pulmonary fibrosis patients. There is no cure for pulmonary fibrosis (PF), but there are treatments that can slow down the progression of the disease and help patients…
The Pulmonary Fibrosis Foundation’s 2017 Summit, where pulmonary fibrosis researchers and community members from around the world can share information and experiences, will be Nov. 9-11 in Nashville, the foundation announced. Summit organizers encourage researchers, physicians, academics, industry leaders, patients and caregivers to take part in the sessions, which will highlight developments…
