Australian and German companies, AdAlta and  XL-protein, have entered into a collaboration to create a long-acting form of AdAlta’s AD-114, an antibody-based treatment for idiopathic pulmonary fibrosis (IPF) and other fibrotic conditions. According to the agreement, XL-protein will contribute with their PASylation technology, attaching a string of amino acids that…
Windtree Therapeutics recently presented preclinical data supporting the potential effectiveness of its KL4 surfactant against acute and chronic lung injury and fibrosis induced by exposure to radiation. The data were presented at the 62nd Radiation Research Society (RRS) Annual Meeting, that took place in Hawaii in October. KL4 is a synthetic, peptide-containing surfactant structurally similar to the…
Exercising and keeping as fit as possible is encouraged for everyone, but especially for people with pulmonary fibrosis. Regular exercise has been shown to help pulmonary fibrosis patients, and keep stress levels low and improve sleep. Here are nine ways to motivate yourself to get out there and start exercising, based on tips…
Jordan Howard, the lead rusher for the Chicago Bears football team whose father died of pulmonary fibrosis (PF), will announced his intent to be a PF advocate and supporter of efforts to better treat and cure the disease today at the 2016 Pulmonary Fibrosis Foundation (PFF) Volunteer Meeting in Chicago. Howard’s father, Dr. Reginald…
Pulmonary fibrosis is a lung condition that causes scarring of the lung tissue which results in difficulty breathing. Did you know that pulmonary fibrosis can be difficult to diagnose and treat? In this video by Boehringer Ingelheim Idiopathic Pulmonary Fibrosis,…
I don’t know about you, but for me adjusting sure is hard. I just got back from a visit to University of California, San Francisco, for my six-month check-up at the Interstitial Lung Department. It’s one of three places in California where lung transplants (along with Stanford…
With winter just around the corner, it’s time we all started to look after ourselves a little more. Avoiding germs is one thing, but we can also try and boost our immune systems by getting plenty of sleep and eating the right foods. Here are nine foods known for their…
For people who have pulmonary fibrosis, lung transplantation can be a viable choice for extending their lifespan and improving the quality of their life. In this Loyola Medicine video shared in December 2013, Dr. Daniel Dilling and nurse Karen Pelletiere talk about what happens to a patient after they undergo…
An extract from an earthworm reduced inflammation and fibrosis in the lungs of mice exposed to silica, acting through known antioxidant and anti-inflammatory molecular pathways. The findings suggest the extract could be explored as a potential drug therapy for silicosis. The study, “Earthworm extract attenuates silica-induced pulmonary…
Inhibiting PARP-1 protein expression eased several symptoms of lung fibrosis in a mice model of the disease. These results suggest that PARP-1 inhibitors may carry therapeutic potential for patients with idiopathic pulmonary fibrosis (IPF). The study, “HYDAMTIQ, a selective PARP-1 inhibitor, improves bleomycin-induced lung fibrosis by dampening the TGF-β/SMAD signalling…
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