Log In or Register to Join The Conversation!
Viewing 15 reply threads
  • Author
    Posts
    • #21888
      Mark Koziol
      Keymaster

      While reviewing hot topics on our forum pages I came across a topic written by our own Charlene Marshall. The topic is titled; Gabapentin for IPF- Related Cough? There were many responses to this topic in the last month. I found several publications supporting the use of Gabapentin for “refractory chronic cough”. Unfortunately, this is one of the symptoms many IPF patients suffer with. The article; “Chronic Cough: Our Approach to Diagnosis and Treatment” appeared in the Cleveland Clinic’s Respiratory Institutes website. Dr. Rachel Taliercio authored the article and writes, “Gabapentin has been shown to improve cough-specific quality of life in patients with refractory chronic cough, suggesting that central reflex sensitization is involved in this syndrome.” Although the article doesn’t specifically mention IPF it does give a concise perspective on chronic cough.

      When I take medicines prescribed to me, I try and educate myself on their properties and side effects. I feel I should know everything about them before I begin to take them. In her article Dr. Taliercio states, “Educating patients about possible side effects and having a protocol to guide titration of therapy is essential. Equally important is early referral to a speech pathology specialist. This therapy is an effective nonpharmacologic modality for the management of chronic cough.” I do know of several persons who are taking this medicine and have seen a speech pathologist to control the coughing.

      I found an article published in The Lancet. The article is titled; “Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial”. There is a charge if you would like to read the entire article but I feel the summary that is linked is sufficient. In this trial the gabapentin “is both effective and well-tolerated”.

      As a forum member and co-moderator I am grateful for our members who are constantly bringing attention to other treatments that others may not have heard of. Will the results, I have stated here persuade you to ask your physician about gabapentin? 

       

    • #21899
      George Quartell
      Participant

      Mark, thanks for this post.  However, in my research in drugs.com, webmd.com, and others, there appears to be a significant amount of effects that my overall condition would not tolerate: I am diabetic, I’m on antidepressant medication, and I have a condition of gastrointestinal bleeding.

      One more comment for those wishing to pursue the use of Gabapentin further, there are three different brands of this drug: Gralise, Horizant, and Neurontin.  Which of these are you focused upon?

    • #21908
      Mark Koziol
      Keymaster

      Hello George, thanks for writing. I appreciate your comments. I am not focusing on any of the brands but I wanted to share how the use of Gabapentin has the ability to control refractory chronic cough. I am glad you brought the differences of the brand names to our attention. Patients are sometimes able to take one brand preferably over another. Thank you, mark.

    • #21915
      Wendy Dirks
      Participant

      I have my next appointment at the hospital in less than two weeks and one of the things I want to discuss is my cough. I’m not sure what “chronic” means in this context, but I have intermittent spells of coughing that have become so severe that I’m getting muscle spasms afterward around my rib cage. They are very painful. I’ll see what the consultant says.

      • #21916
        Mark Koziol
        Keymaster

        Hello Wendy, I can relate to what you are saying. I suffered through these same coughing spells pre-transplant. Hopefully your consultant can help with your cough. Mark

    • #21919
      Wendy Dirks
      Participant

      Thanks, Mark – I don’t know what I’d do without these forums! I get so much information here and it is really appreciated.

    • #21921
      Mark Koziol
      Keymaster

      You are most welcome Wendy.

    • #21922
      Bill Turnage
      Participant

      Mark, after reading about this topic, I was planning to ask my pulmonary doctor if I should try Gapapentin for my IPF-related cough. Instead he has recommended trying this drug: Hydrocodone/Chlorpheniramine Polistirex. I’d like to know if any of our forum participants with IPF have been prescribed this medication and if so, what were the results? Side effects? Would they recommend it? The dosage he’s recommending is 5ml every 12 hours as needed. Any information that can be provided would be much appreciated. Thank you very much.

      Bill Turnage

      • #21923
        Mark Koziol
        Keymaster

        Hello Bill, thank you writing. It looks like he has prescribed an opioid for you. Opioids are commonly prescribed and are found to be a successful treatment for the chronic cough that we exhibit as ipf patients. Take care, Mark.

    • #21924
      Bill Turnage
      Participant

      Thank you Mark. I will try it and hope it works.

    • #22492
      Regina Bolyard
      Participant

      I have taken generic gabapentin on and off for years to treat pain. It definitely helps me with cough reflex. I still feel the burning sensation in my lungs, but I can resist the urge easier on this medication.

    • #22493
      Mark Koziol
      Keymaster

      Hello Regina, thank you for sharing your experience with Gabapentin. I know it’s not a panacea for everyone but it has helped many pf patients. Take care, Mark.

    • #22504
      Virginia Currie
      Participant

      gabapentin works for me.  I have been coughing for more than a year until my pulmonologist told me that I can take Neurontin or Gabapentin.  My life improved.  Constant coughing stressed me out.  I take 300 mg three times a day.  I have a decent sleep.  Neurontin helps with sleep.  One side effect is sleepiness.  I took it before during the night time.  I found out with the 300 mg TID doesn’t make me sleepy during the day.  I still work as a registered nurse.  I was just newly diagnosed for PF.  Hope this comment helps.

    • #22505
      Mark Koziol
      Keymaster

      Hello Virginia, thank you for sharing your experience with using gabapentin. I am pleased the medicine works for you. Chronic coughing is a disruption in life no one wants to experience. Take care Virginia, mark.

    • #23104
      Reshma Joshi
      Participant

      Hello

      I see that Gebapentin has worked for many patients but is it available everywhere in the world? We’re from Nepal and my mom has been suffering from chronic cough a lot these days. Her oxygen level is dropping and we’re giving her oxygen at home. So if anyone can plz tell me the availability of this medicine and also what’s the average level of oxygen for the IPF patient? And till which level we don’t need to be afraid?

    • #23105
      Mark Koziol
      Keymaster

      Hello Reshma, you will have to ask your doctor or even a pharmacist if the gabapentin is available in Nepal. Most physicians want you to keep your oxygen saturation above 88%. Doctors usually prescribe supplemental o2 if your saturation keeps going below this standard. Continued low oxygen saturation can cause organs to fail. Optimal saturation is above 95%. Hope this helps. Take care, Mark

    • #23139
      Doug Jones
      Participant

      These response are interesting; glad that gabapentin may work for some.  I note that the research study cited from Lancet EXLCLUDED chronic coughers who had a respiratory disease so its effectiveness for IPF patients may not be the same–see excerpt below.  The medical literature shows mixed results for gabapentin in controlling cough–plus a variety of potentially undesirable side effects.  My doctor declined to prescribe this for me.  Doug

      “This randomized, double-blind, placebo-controlled trial was undertaken at an outpatient clinic in Australia. Adults with refractory chronic cough (>8 weeks’ duration) without active respiratory disease or infection were randomly assigned to receive gabapentin (maximum tolerable daily dose of 1800 mg) or matching placebo for 10 weeks.

      • This reply was modified 4 months, 1 week ago by Charlene Marshall. Reason: formatting to remove code
    • #23164

      Hi Doug,

      Thanks for sharing, as I always appreciate hearing the literature behind some lesser known symptom relievers, such as Gabapentin. I was surprised to hear how many people seem to be helped by this drug for the cough, but excluding the population of chronic coughers associated with lung disease is important information to note, as you say. Thanks for sharing. It does seem that the drug helps a lot of people, but I can understand the hesitation in giving it to others too.
      Take care,
      Charlene.

Viewing 15 reply threads
  • You must be logged in to reply to this topic.
Copyright © 2017-2020 All rights reserved.

©2020 KLEO Template a premium and multipurpose theme from Seventh Queen

CONTACT US

We're not around right now. But you can send us an email and we'll get back to you, asap.

Sending
or

Log in with your credentials

or    

Forgot your details?

or

Create Account